KEYNOTES 

Trustworthy Computing

• Jerry Cuomo, Global Industry SME, xIBM & Professor

The practical applications and primary cost determinants associated with deploying AI models
in precision medicine within Clinical and Research environments; and how the combination of
L1& L2 derivative protocols empower these benefits.

Title: TBA

• Shahram Ebadollahi, Founder & Principal, Nav.AI

AI Supplement for Cyber Risk Oversight Handbook & Best Practices

• Larry  Clinton, President and CEO, Internet Security Alliance (ISA)          

In this high-impact keynote, Larry Clinton will present the latest findings from the AI Supplement to the National Association of Corporate Directors’ (NACD) Cyber Risk Oversight Handbook, which ISA co-authored. Tailored for healthcare executives and innovators, the session will provide a strategic roadmap for integrating AI safely into decentralized healthcare systems. Attendees will gain a framework for risk governance, resilience building, and accountability when deploying AI-driven health technologies.

AGI vs. Decentralized AI: Why Decentralized AI Is the Future of Healthcare

• Ki-Youn Jung, Co-founder & CEO, EON.HEALTH

Ki-Youn Jung argues that general AI is not the holy grail of healthcare — decentralized, domain-specific intelligence is. In this provocative talk, Jung will contrast centralized articifial intelligence general intelligence (AGI) models with decentralized AI frameworks that are purpose built for healthcare. Using examples from EON.HEALTH’s decentralized care models, she will explore how patient-controlled data, edge AI, and tokenized incentives outperform AGI in reliability, ethics, and adoption.

Executive Strategies for Embracing Emerging Tech Convergence in Healthcare: Looking Beyond GenAI: Collaborative and Personal AI in Highly Regulated Industries

• Amber Hartley, Chief of Strategy Officer, BurstIQ

GenAI is great at summarizing what it learns from source materials. But where did those source materials come from? Human knowledge. In this presentation, learn what AI can accomplish when it gets personal. Organizations are exploring how to engage with people in a more personalized, holistic way, how to let individuals control and extract value from their personal intellectual property through personal agentic AI services, and how to build AI-enabled research communities that fulfill the promise of federated learning and collaborative intelligence. Goals to explore:
– The evolution of AI from generative to agentic to personal
– GenAI, agentic AI, and personal AI use cases in healthcare and life sciences
– Considerations for managing source data in highly regulated industries
– Problems that still need to be solved for widespread adoption of personal AI

FIRESIDE CHATS

Title: TBA

• Shahram Ebadollahi, Founder & Principal, Nav.AI

• Francisco Curbera, Lead, AI Platform Innovation, Swift

Real-World Layer One Blockchain Applications in Healthcare and Life Sciences

• Gianluca De Novi, PhD, CEO, Circular Protocol

• Bert Fernandez, Founder of HealthTech2Care

Layer One blockchain technology is moving into production-grade use cases that address critical challenges in healthcare and life sciences. This fireside chat will explore real-world applications such as certifying medical records in pharmacy networks, creating verifiable audit trails for clinical research data, and enabling drug production traceability. The conversation will cover how blockchain can safeguard data integrity, ensure compliance, integrate public and private chains for different privacy needs, and create a trusted data layer to support AI adoption. Attendees will gain insights into the opportunities and challenges in the healthcare and life

sciences sectors.

PANEL SESSIONS

Web3 for Patient-Controlled Clinical Data: Unlocking Empowerment and Access

As healthcare pivots toward decentralized models, the control and ownership of clinical data are at the heart of the transformation. This powerful panel brings together visionary leaders in data science, regulatory policy, and AI to explore how Web3 technologies—including blockchain, self-sovereign identity, and decentralized data ecosystems—can shift data governance from institutions to individuals. Together, they will unpack the technical, ethical, and policy implications of enabling patient-owned clinical data, and what it means for the future of care delivery, research, and health equity.

Anjum Khurshid, Chief Data Scientist at Harvard Pilgrim Health Care Institute, will explore the intersection of data interoperability, FHIR standards, and decentralized frameworks in empowering patients while maintaining trust and clinical continuity.Dr. Olga Kubassova, President & CEO of IAG, will discuss how Web3 models can enhance data liquidity in clinical research and imaging, enabling patients to contribute real-world data directly to research and trials with privacy and provenance intact.Ajaz (AJ) Hussain, Regulatory Science Advisor and former FDA executive, brings critical perspective on the evolving regulatory landscape, addressing how Web3 applications must navigate legal, ethical, and compliance challenges to achieve patient data empowerment.Brian Ahier, Chief Data Officer at AI Mind System Foundation, will highlight how AI and decentralized architectures converge to unlock real-time insights from distributed datasets—paving the way for more inclusive, adaptive, and patient-driven healthcare systems. 

Cybersecurity, Identity & Infrastructure: Securing Healthcare’s Platform Defense Strategies for Web3 and Beyond

As healthcare systems embrace decentralized technologies, the attack surface expands—making cybersecurity, digital identity, and infrastructure resilience more critical than ever. This expert panel explores how healthcare organizations must evolve their defense strategies to secure data, platforms, and users in the age of Web3. This session dives into what it takes to build a secure and ethical digital foundation for healthcare—one that protects patients, empowers providers, and scales with innovation.

Anvesh Gunuganti, Information Security Engineer at Optum, brings hands-on experience protecting large-scale health networks, offering insights into how zero trust, multi-factor identity, and blockchain-based access control are reshaping cybersecurity baselines.Taha Sajid, Founder of Xecurity Pulse, will unpack emerging threats and proactive countermeasures across decentralized systems—from smart contract vulnerabilities to secure interoperability between legacy and Web3 platforms.Julie Saslow Schroeder, JD, LLM, a global compliance and risk expert, will illuminate the intersection of regulatory frameworks, legal accountability, and platform governance, especially as patient data moves across borders, clouds, and decentralized nodes.

Decentralized Strategy, Policy & Leadership

The transition from siloed legacy systems to decentralized healthcare infrastructure requires more than just technology—it demands strategic vision, cross-sector leadership, and public-private collaboration. This powerhouse panel brings together trailblazers in blockchain, enterprise architecture, and digital trust to explore how decentralized technologies are redefining healthcare’s operational and economic landscape.

This session will arm executive leaders, policymakers, and innovators with actionable insights into what it truly takes to lead the decentralized healthcare transformation—technically, operationally, and ethically.

Jai Singh Arun, Chief Product Officer at IBM, will outline how platform-based thinking is transforming health enterprise strategy—shifting organizations from fragmented digital assets to scalable, modular ecosystems designed for transparency, interoperability, and rapid innovation. Jerry Cuomo, former IBM Fellow and recognized industry SME, will take a deep dive into the architecture of digital trust—explaining how decentralized identity, verifiable credentials, and immutable ledgers can power secure, scalable health systems ready for real-world deployment. Nitin Gaur, a respected blockchain infrastructure and investment expert, will explore how decentralized platforms are rebuilding the healthcare value chain—from procurement to payment, data exchange to discovery—unlocking new economic models and policy frameworks for global health equity.

Supply Chain, Audit, and Systems Integrity for Life Science Resilience, Transparency, and Trust

In an era of increasingly complex global supply chains, ensuring transparency, traceability, and trust is more critical than ever. This session will explore how emerging technologies such as blockchain, artificial intelligence, and digital audit frameworks are transforming supply chain management and enhancing systems integrity. Speakers will dive into real-world applications, discuss best practices for achieving end-to-end visibility, and examine how decentralized solutions are redefining auditability and accountability across industries. Attendees will gain valuable insights into building resilient, transparent supply chains that can withstand disruption while maintaining the highest standards of integrity.

• Justin Goldston, PhD, Professor, Georgetown University

• Rakesh Parameshwar , Former Head of Strategic Initiatives, Moody’s, CEO, Niva Horizon

•  Mohan Venkataraman, Principal Consultant, Block10.ai

Bridging Academia and Innovation: Circular Economies and the Future of Decentralized Systems

The decentralized healthcare revolution is not just technical—it’s conceptual, grounded in evolving academic research and economic theory. This thought-provoking panel brings together academic leaders and real-world innovators to explore how circular economy models and decentralized systems can reshape healthcare infrastructure, sustainability, and value creation.

In this cross-disciplinary dialogue, discover how research and theory are powering practical breakthroughs in decentralized healthcare.

Roman Beck, Professor at Bentley University and leading voice in blockchain governance, will unpack the theoretical foundations of circular value exchange in decentralized health ecosystems—where trust, data, and incentives circulate beyond institutional boundaries. Dr. Justin Goldston, Professor at Georgetown University and blockchain-in-healthcare expert, will explore how academic research is catalyzing innovation in decentralized clinical trials, supply chain transparency, and equitable data monetization. Anjum Khurshid, Chief Data Scientist at Harvard Pilgrim Health Care Institute, will share insights on bridging FHIR standards and data equity frameworks with decentralized architectures that prioritize patient agency and system-wide utility. Moderated by Gianluca De Novi, CEO of Circular Protocol and a champion of tokenized circular economies, the session will explore how academic rigor and entrepreneurial experimentation are converging to build next-generation health platforms.

The CDHLS Blueprint: Realizing Decentralized Healthcare and Life Sciences at Scale

This flagship session, presented by the Coalition for Decentralized Healthcare and Life Sciences (CDHLS), delves into the future of healthcare decentralization — where patients control their data, care delivery is democratized, and innovation is driven by interoperable, secure, and inclusive platforms.

From blockchain-based infrastructure to circular economies and Web3 governance, panelists will explore real-world implementations, policy shifts, and enterprise adoption models redefining the future of global health.

Attendees will gain insight into CDHLS’s ongoing initiatives and how collaboration across academia, startups, enterprise, and government is building a patient/consumer centric, tech-enabled health future — one that is open, secure, and inclusive by design.

• Gianluca De Novi, PhD, CEO, Circular Protocol

• Filippo Frangioni, Head of Partnerships, Nordic Blockchain Association

• Jim Nasr, CEO, Acoer

• Nitin Gaur, xIBM and Industry SME

• David Stefanich, CEO, Waivedx.ai

DeSci: How Tokenization Can Speed Up Molecule Research and Development

• Dr. Adel ElMessiry, MHG Board Chairman, AIVP Founder
•  Jelani Clarke, PhD, Executive Lead, DeSci World

The decentralized science (DeSci) movement is reshaping how innovation happens in the life sciences. This panel will explore how blockchain-based tokenization can revolutionize the molecule research and development process—from early-stage discovery through clinical trials and commercialization. Industry experts, DeSci pioneers, and biotech innovators will discuss how tokenized assets can represent intellectual property, research milestones, and funding stakes, enabling faster capital formation, transparent progress tracking, and global collaboration. The discussion will highlight case studies where tokenization has reduced time-to-market, improved researcher incentives, and democratized access to scientific breakthroughs. Attendees will gain insights into the technological, regulatory, and economic frameworks that make tokenization a game-changer for accelerating medical and biotech innovation.

AI, Data & Platform Economics: Building the Infrastructure for Decentralized Healthcare Intelligence

As the healthcare landscape shifts toward decentralized, patient-centric models, the convergence of AI, data governance, and platform economics is redefining value creation. This panel brings together pioneering leaders at the forefront of AI platform innovation to explore how data ecosystems and intelligent infrastructure are transforming clinical, operational, and economic outcomes in healthcare.

Attendees will gain insights into how platform-based thinking, combined with emerging intelligence layers, can drive equity, scalability, and sustainability in healthcare delivery and innovation.

Shahram Ebadollahi, Founder & Principal of Nav.AI, will examine how AI platform convergence can unlock real-time clinical insights while preserving autonomy and privacy through decentralized architectures. Francisco Curbera, Lead of AI Platform Innovation at Swift, will share strategies for scaling enterprise AI platforms that prioritize ethical design, interoperability, and trust. Brian Ahier, Chief Data Officer at AI Mind System Foundation, will explore how next-generation data stewardship frameworks are critical for enabling AI + Web3 ecosystems to improve population health outcomes.

Innovators, Founders & Emerging Tech: How The Combined Power Of Blockchain, AI, and Quantum Will Shape Healthcare’s Future

A seismic shift is underway in healthcare, driven by the convergence of blockchain, AI, quantum computing, and decentralized finance. This high-impact session brings together three trailblazing founders leveraging next-gen technologies to disrupt outdated systems and deliver future-ready solutions. Join this dynamic discussion to learn how these leaders are shaping the healthcare of tomorrow—creating scalable, secure, and value-based ecosystems that challenge the status quo.

Tony Quinones, CEO of Bright Path, will explore the tokenization of care journeys to power outcome-based reimbursement models—putting patient results at the center of financial models. Chris Langley, COO of CareFi, will dive into how decentralized finance, AI-driven risk models, and tokenized healthcare indices known as synthetics are converging to modernize how we price, transfer, and manage clinical cost and utilization volatility. Michael “Dersh” Dershem, CEO of Apierion, will reveal how distributed data models and blockchain infrastructure can build sustainable bioeconomies that fuel equitable innovation.

Trusted AI in Healthcare: Leveraging Verifiable Credentials (VCs) & Decentralized Identity (DID) for Secure, Transparent, and Ethical Outcomes

• Jim Mason, Chief Solution Architect, Sky Web

As AI transforms healthcare—from diagnostics to insurance claims, drug development, and compliance—trust remains a critical barrier. How do we ensure AI decisions are fair, explainable, and privacy-preserving? This session explores how Decentralized Identity (DID) and Verifiable Credentials (VCs) can enhance trust in AI-driven healthcare systems. We’ll examine real-world use cases, key challenges, and how Self-Sovereign Identity (SSI) and blockchain-based verification can mitigate risks while improving efficiency, transparency, and regulatory compliance.

This session is a must for anyone shaping the future of AI-driven healthcare. Whether you’re a provider, technologist, regulator, or investor, you’ll leave with insights on how decentralized identity and verifiable credentials can build a more trustworthy, efficient, and patient-centric healthcare system.

Blockchain Native Clinical Trials: Real-Time Data, Compliance, and Insights

• Rama Rao, CEO, BloqCube

• Wessam Sonbol, CSM, CSPO, ICP-ACC, CEO, Delve Health

Project Nanda: Towards the Internet of AI Agents

• Ramesh Raskar, Associate Director, MIT Media Lab

• Pradyumna Chari, Postdoctoral Associate, MIT Media Lab

Project Nanda, which originated at MIT, is a collective building open source implementations for an open vibrant agentic web. The project includes research, code base, standards and a venture hub. Roadmap includes trust layers, knowledge pricing, packet switched intelligence, population AI and privateML.

Nanda Quilt is a lightweight index that routes requests to relevant registries, avoiding full centralization. Organizations host their own agent registries (decentralized). The index is hosted at 15 universities and organizations across the globe. The index supports and uses MCP, A2A, NLweb, IoT registries, Web3 agents and even human agents in the loop.

The NANDA quilt registry architecture is a means for discoverability, identifiability and authentication in the internet of AI agents. We present an architecture where a minimal lean registry resolves to dynamic, cryptographically verifiable AgentFacts that supports multi- endpoint routing, load balancing, privacy-preserving access, and credentialed capability assertions. Our architecture design delivers four concrete guarantees: (1) A quilt-like registry proposal that supports both NANDA-native agents as well as third party agents being discoverable via the registry, (2) rapid global resolution for newly spawned AI agents, (3) sub- second revocation and key rotation, (4) schema-validated capability assertions, and (5) privacy- preserving discovery across organizational boundaries via verifiable, least-disclosure queries.

Actuate– Using Blockchain for Global Health Equity

• Dr. Macharia Waruingi, Actuate Biomedicine

• Nikiki T. Bogle, Esq, CEO & General Counsel, Joe Higgs Foundation for Health

Actuate is a blockchain-powered initiative using the Actuate Token to advance global health
equity through the layers of economic, distributive, and social justice. It provides unbanked and
marginalized populations in Africa with digital identity and financial inclusion, ensuring
equitable representation in global systems.

Actuate leverages innovative funding models—such as quadratic funding and retroactive public
goods funding—to channel resources into health infrastructure, decentralized care delivery,
and equitable distribution of biomedical technologies. The token funds and rewards innovators
from historically marginalized communities, turning intellectual capital into financial capital.
This enables local talent to contribute meaningfully to global health solutions—and to benefit
from them.

The Actuate Token also connects the African diaspora by enabling direct investment in
hospitals, maternal care, and health innovation. This creates a circular economy of care
grounded in shared identity, trust, and equity. Actuate is more than a blockchain project—it is a
bold framework for fortifying equity in global health.

Plus more – stay tuned for more speakers and discussions as the program grows!

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